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Sense & Sinsemilla: Is Cannabis Really Good For You?

It’s hard to separate fact from fiction when it comes to the medical benefits of cannabis. ";

When she was 46, a woman we’ll call Hope (who asked to remain anonymous for reasons which will become obvious) was finding it impossible to fall and stay asleep at night. She was working full-time, raising a child with extreme special needs, and dealing with worrisome health issues of her own. 

Since plants cross-pollinate and new varieties are being grown all the time, it’s not always obvious what grows are "hot" and what are "just hemp".

She had Lyme disease, as well as retinitis pigmentosa, a condition which resulted in the loss of vision in her left eye, and herniated disks in her back. On top of all that, Hope was leaving a job she’d had for over a decade to start a new career.

Desperate for rest, Hope tried every sleep remedy she could—from prescription medications like Ambien to holistic remedies like valerian root. When those didn’t work she turned to meditation and hypnosis. Nothing helped.

Sleep-deprived and increasingly anxious, she was miserable.

So when a homeopath recommended she try cannabis, even though marijuana was (and still is) illegal in her state and she was herself the director of an addiction drug clinic, Hope was willing to try anything. Medical marijuana was legal where she lived, but not to treat symptoms related to Lyme or insomnia.

Hope found a secret group of users of medical marijuana on Facebook to advise her and managed to buy organically grown quality-tested cannabis illegally from an internet vendor. 

What responsible growers and health care professionals seem to agree on, however, is that the more high-quality ingredients used in making tinctures and preparations, the more likely they are to have health benefits.

It came in a taffy-like blob which she heated on the stove top with an equal amount of coconut oil. She put the tincture in a bottle, and put one drop under her tongue.

Twenty minutes later she was fast asleep.

“It was the first time I slept really well in years,” she told me when we talked by phone. “I woke up the next day, and it was like heaven … It was incredible. I started to look forward to being able to sleep.”

That was five years ago. Hope has been using cannabis ever since.

When Ballot Measure 91 passed in 2014 the recreational use of cannabis became legal in Oregon. California, though it set the trend to legalize medical marijuana over two decades ago, was the last hold-out on the West Coast to legalize recreational use of pot. Legalization in California came in November 2016 when a majority of voters approved the Adult Use of Marijuana Act. California dispensaries finally started selling marijuana for recreational use on January 1, 2018, to great fanfare. According to the New York Times, some 200 enthusiastic customers lined up at an Oakland dispensary at dawn, eager to buy pot.

Despite enjoying enthusiastic support across the country, cannabis remains illegal at the federal level. The Feds classify it as a “Schedule 1” narcotic, along with heroin, LSD, and ecstasy. Still, with the change in California law, recreational cannabis use is now legal up and down the West Coast, as well as in Alaska.

What that means for Southern Oregon—where I live—is that you’re apt to see dispensaries on practically every other corner in town and acres of fields being planted in rural areas. Just this week my editor reported seeing new hemp fields on North Phoenix Road, West Main Street in Medford on the way to Jacksonville, Taylor Road in Central Point, and along I-5 between Ashland and Medford.

In the midst of this cannabis craze, a robust industry has grown up around the plant—including growers, harvesters, “trimmers” (who process the plants), and retailers. Then there are the graphics on Instagram and Facebook extolling its virtues and the huge billboards on I-5 advertising retail cannabis stores. To say nothing of headlines: “how weed helped me get in the best shape of my life” and “7 incredible health benefits of marijuana.”

Some of your friends and acquaintances undoubtedly believe cannabis is a miracle plant. As one small town city manager told me, “It’s surprising how quickly it’s getting into the mainstream. I was at Easter with my wife’s family and my 85-year-old father-in-law came out with a CBD product. ‘For pain,’ he told us. ‘I use it on my feet!’”

At the same time, you likely have other people in your life who believe cannabis is a leafy devil, leading to spaced-out, unfocused, unhappy people who are at best wasting their money and their time and at worst are shirking their responsibilities, sleepwalking through their lives, and committing crimes after getting stoned. 

Cannabis plants contain over 100 cannabinoids that can affect different receptors, and new cannabinoids are being discovered all the time.

One criminal defense lawyer I spoke to for this article (who also wanted to remain anonymous) hates the stuff and told me cannabis use has been involved in many violent crimes his clients commit.

How do you separate the hype from the health benefits? What’s cannabis actually good for, and what is hot air? For all its uses and proponents, cannabis is a surprisingly complicated plant that’s actually not that well understood.

“When it comes to cannabis I always talk about confirmation bias,” says Matt Vogel, 44, a professional health educator and adjunct instructor at Southern Oregon University (SOU) in Ashland. “People really seek out the information they already believe and that they want to hear.” 

Credit www.matt-vogel.com
Matt Vogel, professional health educator and adjunct instructor at Southern Oregon University (SOU) in Ashland, Ore.

Vogel, who does substance use trainings with community groups, professional organizations, and high school and college students across the country, thinks there’s more bias and emotion surrounding this substance than almost any other. “Sometimes it’s really tricky to get into a rational conversation about it,” Vogel admits.

So how effective is cannabis as “medicine”?

And is using it actually good for your health?

There’s no question that some people enjoy myriad health benefits from using it. But there’s also evidence that cannabis use has its downsides. Keeping in mind that every user has a different experience, that because it’s been illegal for so long cannabis has been understudied, and that new science is emerging all the time, let’s see if we can add some sense to the sinsemilla question.

Cannabis, a Primer

First, some background.

Cannabis is thought to be native to Asia. While some reports say the plant was grown and harvested 12,000 years ago, according to research published this June in the journal Science Advances, the earliest scientifically verified evidence of human consumption of cannabis was found in a 2,500-year-old cemetery in Central Asia (in what is now far western China). Analyzing the contents of wooden bowls at a burial site, an international team of scientists found this Jirzankal cannabis contained psychoactive properties.

The Vikings used cannabis for pain relief during childbirth, according to Barney Warf, Professor of Geography and Atmospheric Science at the University of Kansas, who explained to a journalist at LiveScience that both hemp and psychoactive marijuana were widely used in Ancient China and that cannabis came to North America via the southern route. 

Credit Postcard Collection - Kentucky Digital Library
Cutting Hemp in Kentucky - 1775.

In the Americas the production of cannabis was widespread from the 1600s to the late 1800s. Colonists used the hemp plant to make rope, sails, and clothing. In America in the late 1800s and early 1900s, cannabis was also in many medicines sold at pharmacies.

While some insist there’s a categorical and hard stop difference between hemp and marijuana, taxonomically hemp and marijuana are the same plant. Since plants cross-pollinate and new varieties are being grown all the time, it’s not always obvious what grows are “hot” and what are “just hemp” (which makes growers who need licensing for different products very nervous). Most hemp varieties have very little, if any, psychoactive components, but do contain CBD, “cannabidiol,” which is considered medicinal but not psychoactive.

Vogel explains to me that when you smoke or eat cannabis, it is the resin-secreting flowers of the female plant that contain the highest concentration of the bioactive substance that makes you feel “stoned” or “high.” This substance, delta-9-tetrahydrocannabinol, is better known as THC. You probably knew that already. But what you may not know is that THC is just one of the many cannabinoids that have now been identified, and one of several known to be psychoactive.

What are cannabinoids? These are compounds that are similar to the endocannabinoids naturally produced in our bodies. The human body’s innate “endocannabinoid system” is involved in many aspects of establishing and maintaining health.

This system, according to an international team of researchers from Vermont, Great Britain, and Italy, writing in the science journal PLoS One,

“… modulates embryological development, neural plasticity, neuroprotection, immunity and inflammation, apoptosis and carcinogenesis, pain and emotional memory, and most importantly from the viewpoint of recent drug development: hunger, feeding, and metabolism.”

Translation: Your endocannabinoid system helps you think, fight diseases, feel less pain, eat, sleep, and relax. So when you consume cannabis, the cannabinoids in the plant itself are thought to attach themselves to the innate cannabinoid receptors on cells throughout your body and to help with these processes.

As if that’s not complicated enough, cannabis plants contain over 100 cannabinoids that can affect different receptors, and new cannabinoids are being discovered all the time. So it makes sense scientifically that cannabis may offer a broad range of health benefits.

Buying Weed in Weed

At La Florista on Main Street in Weed, California (a lumber town named after its founder, Abner Weed), customers must stop at the front and show ID. 

The City of Weed gets its name from the founder of the local lumber mill and pioneer, Abner Weed.

The entranceway has a comfy gray couch with white throw pillows on one side and a counter on the other, like a hotel lobby. You have to be 21 to enter.

Walk through the closed doors and inside is a 10,000 square foot retail store where you can buy cannabis products of all kinds, as well as brightly colored hippie dresses, accessories, incense, books, body oils, and more. 

The owner of La Florista, Elizabeth Tabor, 53, tells me between 80 and 150 customers come into the store, which has been open for just over a year, daily.

Tabor is an energetic businesswoman with ambitious plans. Her goal is to transform Weed, an economically depressed northern California town with fewer than 3,000 inhabitants, into a tourist haven. Instead of empty store fronts, she’d like to see an old-fashioned candy store, art galleries, and upscale restaurants.

“I have celebrity A-listers who have stopped here, and they turn around and get back into their cars because there’s no other shopping downtown,” she laments. “Main Street needs to be revitalized. My goal is to bring it back.”

Cannabis for Pain

Tabor, who’s been interested in alternative medicine for over a decade, is outspoken about what she thinks are the most important health benefits of cannabis. She tells me cannabis really helps with pain, and can help people wean themselves down or off highly addictive opioid pain relief, like Oxycontin and Norco.

Cannabis, Tabor insists, is a safer, less addictive, and equally effective substitute pain medication and a much better choice than opioids, though it may take a few weeks or even months to get the dosing right. 

Credit Jennifer Margulis
Elizabeth Tabor, owner of La Florista, believes the popularity of cannabis can help revitalize Weed.

Helping addicts wean off opioids is also a benefit that Paul Thomas, MD, an addiction specialist based in Portland, Oregon, has also seen firsthand. (Thomas and I wrote a book together, The Addiction Spectrum.)

“Cannabis can put you in another place where you’re not focusing on the pain,” explains Jamie Syken, 41, who co-owns Dirty Arm Farm in Southern Oregon with his wife Melissa. “If you’re in a lot of pain, you can still laugh and enjoy yourself. It’s not necessarily a pain killer, but it’s more how it puts your head space.”

Elizabeth Tabor tells me she’s also seen cannabis help people dealing with post-traumatic stress disorders. At the same time, she says, some of the claimed health benefits of cannabis are exaggerated.

“A lot of companies take advantage of the letters ‘CBD’ and exploit consumers,” Tabor insists, mentioning a CBD face mask sold via pyramid marketing that has a minuscule amount of CBD in it. “What the hell good is it going to do in a face mask?”

Perhaps it won’t take away wrinkles, but 2016 research published in the Journal of Pain found that cannabis lotion given to rats trans-dermally offered relief from inflammation and pain, lending credence to reports that cannabinoids help with arthritis.

Canada’s Arthritis Society estimates that two thirds of Canadians who use medical cannabis use it to manage arthritis symptoms. At the same time, a 2019 review article published in the journal Current Opinion in Rheumatology this April found that some cannabinoids have an anti-inflammatory effect while other cannabinoids may actually promote inflammation. The researchers, calling for further research, conclude: “Cannabinoids might be a suitable treatment for rheumatoid arthritis, but it is important to target the right receptors in the right place.”

Cannabis for Cancer and Seizures

As anyone who’s gotten the munchies from smoking pot can confirm, cannabis has long been used as an effective appetite enhancer and nausea inhibitor, helping patients who are trying to gain weight or who are undergoing chemotherapy. Research has also shown that using cannabis oil on basal cell skin cancers can inhibit tumor growth.

Another area where users and scientists seem to increasingly agree is the usefulness of cannabis in people who suffer from seizures, as well as to treat severe symptoms—like head-banging, self-harm, and other out-of-control behaviors—associated with autism.

“Cannabis seems to be really beneficial to things that are really hard for traditional medicine to treat,” Melissa Syken, 41, co-owner of Dirty Arm Farm, puts in. I interviewed the Sykens (whom I first met when they owned Growing Green Baby in Ashland) while they were driving back from their processing facility in White City, Oregon.

Melissa tells me that their customers with nerve disorders, autoimmune conditions like multiple sclerosis, and cerebral palsy have benefited from cannabis products.

But, the Sykens both insist, quality matters. A lot. Dirty Arm Farm, which has an 11,500 square foot greenhouse and harvests three times a year, tests its products for pesticides and fungicides, as well as for potency. 

Credit Photo courtesy of Dirty Arm Farm
Jamie and Melissa Syken of Dirty Arm Farm, in their 11,500 square foot greenhouse.

While most producers dry the plant first, Jamie and Melissa explain that Dirty Arm Farm uses fresh cannabis—not dried—to make their products. The Sykens say that this practice is essential to preserving the plant’s terpenes and keeping cannabinoids from degrading.

“It’s like fresh fruit versus dry fruit,” Jamie explains. “By processing it fresh-frozen you’re giving people as much of a full spectrum effect as possible.” The Sykens caution against buying CBD products that are made from an isolate instead of a full spectrum of cannabinoids. Jamie says that inferior products made from old and degraded plant material, whether cannabis or hemp, are unlikely to be medically helpful.

“You want the cannabis with the ‘entourage effect,’ which means you have all the cannabinoids that that plant produced, as well as all the terpenes … and [the thousands of] unidentified chemicals in the product,” Jamie says. “All that is gone when you make an isolate. You’re literally left with a white powder. All the medical miracles we’ve been hearing about … are from medical marijuana, not isolates. Not the Diet Cannabis that they’re pushing now.”

Kenneth Palfini, 67, owner of Farmers Insurance in Mount Shasta, California, has firsthand experience with medical marijuana. Palfini, who is also Mayor of Weed, tells me he’s used cannabis on and off for 50 years. In 2007 when he was fighting leukemia he used cannabis as a way to relax. After the cancer went into remission, he continued to use it recreationally.

“My use is similar to someone’s use of alcohol,” Palfini, who describes himself as a lifelong conservative, explains. “I don’t drink very much but every once in a while I’ll have a beer, and every once in a while I’ll have a toke.”

As much as Palfini believes the legalization of cannabis is good for Weed’s economy, he also admits that between 30 and 40 percent of his constituents in Siskiyou County are not happy about having marijuana in Weed. These folks believe cannabis is a gateway drug to heroin and other bad behaviors. They’re also afraid children will have easier access and be more likely to try it.

“It’s founded in a lot of emotion,” Palfini says, insisting that kids have always had access to cannabis, even before it was legalized, and recommending parents stay vigilant. “Part of parenting is being aware.”

Keep Cannabis Away From Kids

But the concern that children and young teens could be harmed by exposure to cannabis is one that many people share. One parent tells me that a neighbor’s 9-year-old spent two days vomiting after eating a bar of “special chocolate” the parents left on the coffee table. That was an accidental ingestion. But there’s a growing body of scientific research showing that the younger you are when you start using cannabis the more problematic it can be.

Matt Vogel from SOU is concerned about children getting access to high potency concentrates and using too much of an edible. It can take a long time to feel the effects of edibles, Vogel explains, and inexperienced users may inadvertently eat too much. 

The concern over marijuana edibles is from getting too much THC. From so-called "gummy bears" to brownies, these consumables appeal to all ages.

This happened to my friend’s elderly mother, who ate so many cannabis cookies (because she didn’t feel any effect) that she woke up in the middle of the night stoned, panicked, and having heart palpitations. “The effects of taking too much can be psychologically devastating,” Vogel adds.

But, he goes on, the biggest concern is not a bad trip. Cannabis use in young people has been correlated with schizophrenia. Vogel calls this a “chicken and the egg question,” as we don’t know if young people prone to psychosis seek out cannabis to self-medicate or if young people who would not suffer from psychosis become psychotic from cannabis use. Regardless, studies have consistently shown that the younger you are when you start using cannabis the greater the chance of suffering from schizophrenia, bipolar affective disorder, and psychotic episodes.

I ask my 20-year-old, who’s majoring in psychology in college, what she thinks about young people using cannabis. She has friends who suffer from mental health issues. They don’t have medical marijuana permits and recreational marijuana had not been legalized in New York. Though New York moved to decriminalize marijuana use just as this article was going to press, her friends had been using it illegally. Some in order to get through the stress of being at a high-pressure school. Others use it in place of anti-depressants.

“They’re self-medicating for depression and anxiety,” Hesperus says, adding that she knows at least half a dozen people, mostly in their twenties, who smoke weed more than five times a week. “Inhaling plant debris is obviously not good for your lung health,” she says. But, she continues, it’s easier to be around these friends when they’re stoned because they’re more relaxed.

Jamie Syken believes one of the best health benefits to cannabis is its psychoactive effect. “When you’re stressed, it feels like there’s no way to escape yourself,” he says. “Sometimes it’s hard to stop beating ourselves up. There’s no hang-over and it literally can allow you to relax. The absolute biggest thing with cannabis is life-quality improvement.”


The ABCs of Cannabis’s Medical Benefits

It’s hard to separate fact from fiction when it comes to the medical benefits of cannabis. What responsible growers and health care professionals seem to agree on, however, is that the more high-quality ingredients used in making tinctures and preparations, the more likely they are to have health benefits. If you try a product and it doesn’t work, the quality may be to blame. If you think cannabis might help you, consider trying different products until you find one that works.

Potential health benefits of cannabis include:

  • Aiding with anxiety
  • Battling symptoms associated with autism
  • Curtailing vomiting and nausea
  • Decreasing insomnia and restless sleep
  • Easing epileptic seizures
  • Exciting the appetite
  • Fighting (lessening) symptoms related to cerebral palsy and Lou Gehrig’s Disease (ALS)
  • Getting a handle on pain
  • Helping the body fight some cancers
  • Improving irritable bowel syndrome
  • Increasing sexual desire

Potential Harms of Cannabis

Most daily users insist that cannabis is harmless, which it may be for them. But, like with any other medicine, whether plant-based or synthetic, side effects have been reported. The most extreme condition affecting heavy users is cannabinoid hyperemesis syndrome. This poorly understood problem results in cyclical episodes of severe nausea, abdominal pain, and vomiting. A 2018 study of frequent users at a New York City hospital found that over 30% of those who had smoked marijuana more than 20 times in the previous month suffered from cannabinoid hyperemesis syndrome. CHS, which is worsened by using more, can be treated with IV fluids for dehydration and with hot baths or showers to lessen the symptoms.

Other potential harms of cannabis include:

  • Anxiety and panic attacks
  • Agitation
  • Coordination issues
  • Depersonalization: a disorder where you feel detached or estranged from yourself
  • Derealization: a disturbance where you experience the world as unreal
  • Dry mouth
  • Hallucinations
  • Impaired reaction time, performance, and judgment
  • Inability to plan
  • Increased risk of other addictions
  • Increased risk of schizophrenia
  • Increased impulsivity
  • Lack of motivation
  • Poor attention
  • Poor memory and decreased ability to learn new things
  • Psychosis
  • Red eyes
  • Tachycardia (fast heart beat)

A regular contributor to the Jefferson Journal, Jennifer Margulis graduated from Cornell University, earned a Master’s degree from the University of California at Berkeley, and a PhD from Emory University. She is a science reporter and book author and her articles have been published in the New York Times, the Washington Post, and on the cover of Smithsonian Magazine. Her most recent book, The Addiction Spectrum: A Compassionate, Holistic Approach to Recovery (HarperOne), is co-authored with Paul Thomas, MD, and includes a chapter on cannabis. Some of the material in this article was adapted from that book. Learn more at www.JenniferMargulis.net.

Jennifer Margulis, Ph.D., is a regular contributor to the Jefferson Journal and also produces radio features for JPR. She's a former senior fellow at the Schuster Institute for Investigative Journalism at Brandeis University. Her writing has appeared in the New York Times, the Washington Post, and on the cover of Smithsonian magazine.